The Seignalet Diet PLUS  (pronounce it "Saynyalay")


Dr. Jean Seignalet

Dr. Jean Seignalet, (photo taken at the beginning of his diet trials)

Here are Dr. Seignalet's "disease tables" showing the success rate for each of 91 diseases

Table 1. Autoimmune diseases (35)

Table 2. "Clogging diseases" (29)
....Osteoarthritis, Diabetes 2, Migraines, Overweight, Parkinson's, Fibromyalgia, Depression..........etc.etc.etc.

Table 3. "Elimination diseases" (24)
.............Colitis, Crohn's, Psoriasis, Hay Fever, Mouth Ulcers, Asthma, Eczema, Acne.....etc. etc. etc.

Table 4. "Complex diseases" (2)
SAPHO syndrome, Behçet's

UK & Europe
US and rest of the world

Ankylosing Spondylitis

Number of Ankylosing Spondylitis patients treated with the Seignalet diet over a period of 20 years : 122

100% remissions: 76     80/90% improvements: 40

50% improvements: 0     Failures: 6     Success rate: 95%

Dr. Jean Seignalet (Pronounce it “Shon Saynyalay”) was a French professor of medicine who devised and trialled a “hypotoxic” diet with 2,565 patients with 115 different, so called “incurable” diseases over a period of twenty years. 91 of the diseases responded to treatment with the diet and there were 1,631 complete remissions. 2,300 patients improved. The diet was not originally intended to be for weight loss but this was found to be one of the many beneficial side-effects, including increased mental alertness and poise, lowering of cholesterol and many other good things including avoidance of heart attack and stroke, cancer and Alzheimer's!

Newly diagnosed?

Are you newly diagnosed with Ankylosing Spondylitis? (Writes Chris Parkinson, translator and agent for the Seignalet family). Are you dreading a lifetime of taking powerful and potentially dangerous drugs to control it? What if the drugs don't work? Or don't work very well? Have you googled the side effects of the drug your doctor is prescribing? (If not you should do so). Do you want to avoid those side effects ?

Or had Ankylosing Spondylitis for some time?

Or have you had Ankylosing Spondylitis for some time and are now looking for a natural therapy or diet to help reduce your dependence on powerful and potentially dangerous drugs and their nasty side effects or come off them altogether? Or have you tried all the drugs available and none can control your own Ankylosing Spondylitis?

Is there a natural way to reverse Ankylosing Spondylitis?

What if there was a diet which could actually reverse Ankylosing Spondylitis? It would surely be too good to be true wouldn't it? Surely only a powerful drug can stop that dreadful pain or other distressing symptoms? What if the only side effects of the diet were clear skin, abundant energy, a svelte figure, perfect mental poise and equilibrium, prevention of cancer, Alzheimer's, high cholesterol and heart disease in later life, increased longevity free from disease, and a host of other health benefits? This must be snake oil surely? But what if it was clinically trialled by a French professor of medicine with two and a half thousand volunteer patients over 20 years, during which the above benefits were demonstrated and meticulously recorded?

Hype, wrong information, misinformation and reality

All of us are constantly bombarded with hype about the latest “fad diet” or this and that magic supplement and in the US, where drug companies are allowed to advertise, the ads promoting a drug for Ankylosing Spondylitis will tell you to avoid “fad diets”. They would say that though wouldn't they? Even if they knew that there was a diet which worked. You may also have read somewhere or been told by your doctor or the charity for Ankylosing Spondylitis (even on other pages on the google results page for your search) that there is no known cure for Ankylosing Spondylitis and no diet which has been proved to work for Ankylosing Spondylitis and you may even have been told to avoid being taken for a ride by “snake oil pedlars” or “medical magical mystery men”.

A diet which can reverse Ankylosing Spondylitis

Let's be clear. It is quite true that there is no cure because Ankylosing Spondylitis has a known genetic component. Yet we say that there is a diet which can reverse Ankylosing Spondylitis because in addition to the genetic component over which you have no control, there are environmental, triggering factors which you can control. One of those environmental factors is your diet. Are we selling snake oil? It's all very confusing isn't it? How do you know who to trust for unbiased and scientifically trustworthy information? Everyone has their own agenda don't they? Whether it's out in the open or hidden. Like everyone else we too have an agenda and it's not a hidden one. The agenda is to give you the information you need to reverse your disease. How much would you give to be able to do that? $5,000? $20,000? $100,000? Re-mortgage your house? Keep your money! Spend it on a good vacation (“holiday” for us Brits) and get a good tan, a real one - remember tans? (see further on). All the information you need is in a 10 dollar book. So if we are snake oil pedlars we're not very good ones are we? There must be much better ways to get rich selling snake oil than selling a book. By the way, if you think we are snake oil pedlars, feel free to tell us so. There is an open forum on this site and we promise we won't delete your post. Those results you see at the top of the page are genuine I can assure you, so if you think this is quackery you are mistaken but there are some caveats. Here they are:

  1. 1. Depending on how you eat at the moment you may have to make big changes in the way you eat, particularly if you are eating the “SAD” diet. (Standard American Diet). For the diet to work properly it has to be strictly adhered to, 100%. If you are currently following any of these diets: Paleo, Weston-Price, raw food, food combining, gluten free, dairy free, the transition to the Seignalet diet will be fairly easy however. 

  2. 2. There will be a period of disintoxication as your body heals itself. This may result in some unpleasant effects like headaches, nausea or a loose bowel. These “detox” effects are only temporary however, and are actually welcome signs that your body is healing itself. To keep these symptoms to a minimum, the different elements of the diet can be introduced one by one, in stages, and if the detox effects become uncomfortable, the transition to the diet can be slowed down or even halted for a while until they pass before resuming at a sensible pace. 

  3. 3. If you are on medication, you must not suddenly stop taking it. Once the diet starts to work however you may want to gently taper off the drugs with the consent of your physician. A large majority of Dr. Seignalet's patients achieved complete remissions or very close to it and were able to come off their medication. Some however, only achieved 50% success and a few had no improvement at all. In case of less than 100% remission you may have to continue taking some medication, although hopefully a reduced, or much reduced dose.

Don't come to regret in a few years time that you did not pay proper attention to this page!

Is this information trustworthy? Well you can purchase this book written by Dr. Seignalet's daughters, one of whom is a medical doctor and judge for yourself, or you can carry on reading this site, there is lots of good stuff on here and it's free. If you are not quite ready to buy the book, don't shut this page down yet because this is your one big chance. Keep reading. Don't dismiss this as hype, only to find out years later that others did it and it does work and you've endured years of needless suffering for nothing. Or if you do close the page down, bookmark it first and then come back to it later when you have time to read the site at leisure, properly.

This new book by Dr. Seignalet's daughters, one of whom is a doctor, is called: “How to prevent reverse 100 diseases the new French way with Dr. Seignalet's diet miracle.”

Its a short guide to Dr. Seignalet's 700 pageScientific and Medical textbook called “Nutrition, the third medicine” (L'Alimentation ou la troisieme medecine), currently in course of translation. Don't be fooled by the modest title by the way, Seignalet proved that nutrition is the first medicine.

If you are now ready to buy the book, don't let me hold you back, click on these links or on the book images in the side panel. If you are not yet quite ready, carry on reading.

UK & Europe
US and rest of the world

For smartphone users, here are Dr. Seignalet's results tables for the 91 diseases he treated successfully with the diet (for desktop/laptop user, see links in the right hand side panel:

Tables show the rate of success for each disease with 100% remissions, 80/90% improvements 50% improvements, failures and percentage success rate (50% improvements are counted as successes). Each table shows all the diseases in Dr. Seignalet's 4 types of disease classification, "Autoimmune, Clogging, Elimination, Complex

Table 1. Autoimmune diseases (35)

Table 2. "Clogging diseases" (29)
....Osteoarthritis, Diabetes 2, Migraines, Overweight, Parkinson's, Fibromyalgia, Depression..........etc.etc.etc.</br>

Table 3. "Elimination diseases" (24)
.............Colitis, Crohn's, Psoriasis, Hay Fever, Mouth Ulcers, Asthma, Eczema, Acne.....etc. etc. etc.</br>

Table 4. "Complex diseases" (2)
SAPHO syndrome, Behçet's</br>

Is it easy? No. But it's not that difficult either!

 We don't want to brainwash you with clever advertising or subliminal messages. We hope you will use all your critical faculties. You will need them because we can give you the tools but you will have to do this by yourself. We are not going to pretend that it's easy but it is probably a lot easier than you think and we promise you that the rewards will make the effort worthwhile. If you are motivated, we promise you can do it. We know from 20 years experience in France that you may start to see results straight away or it may take a little time. Many thousands of French men and women have already seen those results but we cannot do it for you.

Our Cro Magnon ancestors did not have Ankylosing Spondylitis

 So what is this all about? (This is fairly long by the way but keep reading – it's interesting.)

In 1868 in Southern France about 100 miles inland, due east from Bordeaux, in the Dordogne, five fossilised skeletons were found in a rock shelter by a geologist. These remains were clearly early “modern” humans, homo sapiens. Since then, more and more remains have been discovered in Europe, Asia and the American continent and the very earliest have been carbon dated to 45,000 years ago. The location of the first remains at Cro-magnon has given the name to these early humans (although the proper scientific name is European Early Modern Humans or Early Modern Humans). Scientific techniques, especially in the last 20 years, have allowed us to learn more and more about them. We can learn an astonishing amount about their diet from coprolites (fossilized faeces) which can be soaked in sodium biphosphate to reconstitute them for microscopic analysis. From their bones and teeth we can learn about their health, at what age they died and often, what caused their death. Recently scientists have even been able to gene sequence their DNA and a recent discovery, thanks to recovery of DNA recovered from remains and gene sequencing shows that some of them bred with Neanderthals, an early human species which died out, and that we all have some Neanderthal DNA in us.

A light bulb may by now have been switched on and you are thinking: “Oh, the paleo diet, I know all about that”. You may even eat the Cordain/Wolf way yourself. Whoa, hold your horses. We are not there yet. We are going to a slightly different destination. So bear with me, even if you know all this stuff.

So what does this have to do with my condition? Bear with me, all will be explained. By the way, if you want to cut to the chase and buy the book, here are those links again.

UK & Europe
US and rest of the world

 Anyway, to resume my story:

Early modern human remains in Europe, in Asia and on the American continent all show the same things:
  1. 1. These early modern, stone age humans were hunter gatherers. 

  2. 2. Their diet was completely different to ours. 

  3. 3. Although they had tough lives and the bones often show signs of trauma that has healed, (meaning that someone was looking after them during the healing process), they were largely disease free. (Yes, sometimes lunch wasn't quite ready to become lunch and fought back!) 

  4. 4. Not only were they largely disease free, they were superb human specimens compared to ourselves. They were fit and athletic. Their bones were much sturdier than ours, evidence for strong musculature. Their brains were larger and their skeletons were on average around a foot taller than the skeletons of our first neolithic ancestors. Some male skeletons have been found that were over 6 feet 5 inches! 

  5. 5. We are descended from them and the time between them and ourselves in evolutionary terms is the blink of an eye. We have not had time to evolve to function well on a neolithic diet of dairy and cereals (10,000 years ago in the middle east and 5,000 years ago in Europe), then a “modern diet” of refined white sugar and refined white flour (18th and 19th centuries), grain instead of grass fed cows and sheep from the beginning of the 20th century and from mid 20th century onwards, huge amounts of pasteurised cow's milk and dairy and heat and solvent refined vegetable oils and from the 70's onwards a pre-packaged, factory made, junk diet, with enormous amounts of salt, sugar and trans fats, getting more and more devoid of real nutrients until the present day when most of what we eat is just artificially flavoured garbage. It's a wonder we can still manage to drag ourselves around! Try this, watch some footage of crowds at various times of the twentieth century. Notice something? The people in the crowds look sicker and sicker and more and more obese, the closer they are to our own times. (I will find some stock crowd footage on youtube and embed them in a blog page showing this when I have time.) So much for the miracles of modern medicine. As we are genetically identical to them, the difference between this race of the superhuman caveman and ourselves can only be due to diet.

Meet the ancestors! These are reconstructions based on actual remains. This is how this paleolithic mother and daughter would have looked in real life. Look at the superb bone structure of the faces and how sturdy the heads and bodies are. No signs of acne, eczema, or psoriasis either, just clear skin. Just kidding around with the second bit.

Need more proof?

 Accounts of early settlers in the US all paint the same picture of the poor state of health of the scurvy ridden settlers and the superb health and handsome appearance of the native American hunter-gatherers.

From 1671: “ New England's Rarities, discovered in Birds, Beasts, Fishes, Serpents, and Plants of that Country” by Josselyn

A description of an Indian Squa (sic)

The Men are somewhat Horse Fac'd, and generally Faucious, (sic) ie. Without Beards ; but the Women many of them have very good Features ; seldome without a Come to me, or Cos Amoris, in their Countenance ; all of them black Eyed, having even short Teeth, and very white ; their Hair black, thick and long, broad Breasted ; handsome streight Bodies, and slender, considering their constant loose habit : Their limbs cleanly, streight, and of a convenient nature, generally, as plump as Partridges, and saving here and there one, of a model deportment ….”

Let's look at what Loren Cordain says in his book “the Paleo Diet”

“......In other words, built into our genes is a blueprint for optimal nutrition – a plan that spells out the foods that make us healthy, lean and fit. Whether you believe the architect of that blueprint is God, or God acting through evolution by natural selection, or by evolution alone, the end result is still the same: We need to give our bodies the foods we were originally designed to eat.

Your car is designed to run on gasoline. When you put diesel fuel into its tank, the results are disastrous for the engine. The same principle is true for us: We are designed to run best on the wild plant and animal foods that all humans gathered and hunted just 500 generations ago. The staples of today's diet—cereals, dairy products, refined sugars, fatty meats and salted, processed foods---are like diesel fuel to our body's metabolic machinery. These foods clog our engines, make us fat, and cause disease and ill health.........”

 So is this site an advert for the Cordain/Wolf “Paleo (lifestyle) diet”? Not quite. The Seignalet (pronounce it “Saynyalay”) diet was designed by a French Professor of Medicine, Dr. Jean Seignalet.

It differs in a few important respects from Cordain and Wolf's version of the caveman diet (and also from the Western Price Foundation diet come to that). One important difference is that the Seignalet diet was specifically created to reverse chronic diseases and clinically trialled on over two and a half thousand patients over twenty years by a professor of medicine and found to put into complete remission 91 diseases! In addition to reversing disease it can of course also prevent disease and many people in France have adopted it as a lifestyle diet.

Dr. Seignalet (who read, spoke and wrote excellent English which has replaced Latin as the international lingua franca of science and medicine), read Eaton and Konner's seminal 1985 article in the New England Journal of Medicine: “Palaeolithic nutrition. A consideration of its nature and current implications” at exactly the same time as Cordain, ie. as soon as it was published. So there is not even a hair's breadth between what Cordain and Wolf and what Dr. Seignalet consider to be the “original diet”. They all take their cue from Eaton and Konner. Except for one important thing and here it is:

1. Eaton and Konner make no reference to cooking. Cordain and Wolf assume that Early Modern Humans were cooking their meat, which means grilling it over a fire. But for Seignalet, cooked meats and especially grilled meats are a dangerous disease factor. You can see my translation of his chapter on the dangers of cooking on my blog.

Here is (my translation of) what he says in his chapter comparing ancient and modern foods:

“......Fire was invented about 400,000 years ago. However, there is absolutely no proof that fire would have been used to cook food before a recent period, 10,000 years ago. Furthermore, analysis of fossilized faecal remains show that during the Mesolithic, humans ate raw. So we can assume that cooking was little used or not used at all......”

 2. Dr. Seignalet was what the French call an “enseignant/chercheur” (lecturer/researcher). He was paid by the French state to teach medical students but the other part of his job description was to carry out research. What he decided to research and how he carried it out was entirely up to him. Seignalet looked closely at all the foods we eat without any preconceived notions to discover how they are processed by our body and exactly why these non-ancestral foods harm us and it is this work, far more than conjecture about what our ancestors ate, which forms the basis of his diet. Paleo eaters may be surprised to learn for example that he allows rice.

3. Eaton and Konner wrote this in their 1985 article: “Ultimately of course, only experimental & clinical studies can confirm hypotheses about the medical consequences of dietary choices”. Dr. Seignalet took them at their word and only 3 years later, Seignalet was embarking on those studies and 20 years later, he had treated two and a half thousand patients with 115 different diseases, 91 of them successfully, with his diet. With the greatest of respect, no-one in the field of nutrition or medicine in the English speaking world has ever set out to prove their dietary theories like this. They may talk the talk but they don't walk the walk. To my knowledge only the Russians have done anything similar, with their research on fasting. (See my blog article on fasting).

You may have already tried dietary modification for Ankylosing Spondylitis with some success, great or small - or even none at all. Regardless of the results you obtained, please now consider the Seignalet diet. This is to date, the only diet which:

 A. Was trialled over a period of 20 years with over two and a half thousand patients, during which time adjustments were made in the light of results and improved theory.

B. Is the only treatment to have put into long term, complete remission, about 80% of patients treated with 91 different, so called “incurable diseases”.

Here are some links to buy the book if you want to cut to the chase. If not, just carry on reading.

UK & Europe
US and rest of the world

Paris Plage

Vitamin D and Ankylosing Spondylitis

Before I tell you a little bit more about Dr. Jean Seignalet, his diet and the thousands of remissions he achieved with it, I want to talk about how vitamin D could be affecting your health and Ankylosing Spondylitis. Dr. Seignalet's patients were all in lovely France of course and as he was on the French Riviera, a lot of his patients would have come from the South of France also.

“Les congés payés” (mandatory one month paid holiday)

In France, just before the second world war, a left wing coalition of communists and socialists called the “Popular Front” came to power. They brought in legislation whereby all employers in France have to pay for a month's holiday for all their employees every year. You might think that this would be disastrous for France's economy but it was extremely popular with the French population as is the 35 hour work week brought in in 2000. France comes to a standstill in August. Tourists in Paris have the place to themselves. Every summer the Paris mayor's office closes the roads on the banks of the river Seine and ships in tons of sand to put on them so Parisians can pretend they are sunbathing on a beach (its called “Paris Plage” see image). In August the whole population is at a camp site either by the sea or in the mountains. They are out in the sun all day long. Many French people also ski at week ends and in the school holidays. What all this means is that most French people usually have a tan, which means they are getting adequate levels of vitamin d. So for Dr. Jean Seignalet and his French patients, vitamin D deficiency would not have been much of an issue and it is not mentioned in his book: “Nutrition the Third Medicine”

Vitamin D and scare tactics

Since the 1980's, some in the medical establishment have been running a campaign to keep us out of the sun in order to avoid skin cancer. The (British) NHS website has a whole page trying to scare us from letting a single ray from the sun get anywhere near our poor defenceless skin, including this “...Sun damage doesn't just happen when you're on holiday in the sun. It can happen when you’re not expecting it, for example when you go for a walk or sit in your garden....” Yeah, So make sure you stay locked up in your house in the summer holidays. Draw the curtains and whatever you do, don't go on holiday. You will be taking your life in your hands! Get your dog put down because all those walkies add up and you can't afford to risk it. Oh please. For God's sake!

Not a word about the beneficial effects of vitamin D (really a hormone, not a vitamin, made by your skin when UV rays from the sun hit it), particularly how vitamin D deficiency is implicated in nearly all, if not all cancers or the terrible effects of vitamin D deficiency or the fact that pretty well 100% of the British population is vitamin D deficient or even that if you are not getting any sun at all you should at least be taking a vitamin D supplement.

Here is a more measured view:

“Sunlight vitamin D and skin cancer” from: “Anti-cancer agents in medicinal chemistry journal”, Jan 2013

“Today, there is a controversial debate in many scientific and public communities on how much sunlight is appropriate to balance between the positive and negative effects of solar UV-exposure. UV exposure undoubtedly causes DNA damage of skin cells and is a major environmental risk factor for all types of skin cancers. In geographic terms, living in parts of the world with increased erythemal UV or high average annual bright sun (Chris' note: the UK definitely does not qualify here!) results in increased risks of skin cancers, with the greatest increased risk for squamous cell carcinoma, followed by basal cell carcinoma and then melanoma. On the other hand, sunlight exerts positive effects on human health, that are mediated in part via UV-B-mediated cutaneous photosynthesis of vitamin D. It has been estimated that at present, approximately 1 billion people worldwide are vitamin D-deficient or -insufficient. This epidemic causes serious health problems that are still widely under-recognized. Vitamin D deficiency leads to well documented problems for bone and muscle function. There are also associations between vitamin D-deficiency and increased incidence of and/or unfavourable outcome for a broad variety of independent diseases, including various types of malignancies (e.g. colon-, skin-*, and breast cancer), autoimmune diseases, infectious diseases, and cardiovascular diseases. In this review, the present literature is analyzed to summarize our present knowledge about the important relationship of sunlight, vitamin D and skin cancer. “(underlines are my emphasis)

*Note that the authors consider vitamin D deficiency as a cause of cancer. Remember: vitamin D is created by your body when UV rays from sunlight hit the skin. So by staying out of the sun you may actually be more likely to get skin cancer! I think that the truth may be this: skin cancer is caused by dietary factors (Dr. Seignalet's patients had a fraction of the cancers that epidemiology studies for the general population would have predicted – see his “clogging disease” tables) , vitamin deficiency from lack of sunlight on the skin, and when these two factors are in place, sunburn may be a contributory, triggering factor. Dr. Hollick says that a tan (or a dark skin) protects the skin from sunburn. So if your skin is white from lack of sun exposure, your initial exposure for one day should be just 15 minutes or so and you should build up slowly until you have a tan which will protect you.

Here is what the acknowledged expert on vitamin D, Dr. M.F. Holick says:

Vitamin D deficiency: a worldwide problem with health consequences. From the American Journal of Clinical Nutrition April 2008

“Vitamin D deficiency is now recognized as a pandemic. The major cause of vitamin D deficiency is the lack of appreciation that sun exposure in moderation is the major source of vitamin D for most humans. Very few foods naturally contain vitamin D, and foods that are fortified with vitamin D are often inadequate to satisfy either a child's or an adult's vitamin D requirement. Vitamin D deficiency causes rickets in children and will precipitate and exacerbate osteopenia, osteoporosis, and fractures in adults. Vitamin D deficiency has been associated with increased risk of common cancers, autoimmune diseases, hypertension, and infectious diseases. A circulating level of 25-hydroxyvitamin D of >75 nmol/L, or 30 ng/mL, is required to maximize vitamin D's beneficial effects for health. In the absence of adequate sun exposure, at least 800-1000 IU vitamin D3/d may be needed to achieve this in children and adults. Vitamin D2 may be equally effective for maintaining circulating concentrations of 25-hydroxyvitamin D when given in physiologic concentrations. “

You can read the full text here

In Brasil this doctor is putting MS into remission with high dose vitamin D supplementation

(If the English subtitles don't come on, click on the little white box with “cc” at the bottom right of the screen)

Do you get the picture? There is a better than 90% chance that you can reverse Ankylosing Spondylitis with the Seignalet diet. But you will also need adequate vitamin D either from the sun, from a tanning booth or from D3 supplementation. You will also need adequate levels of the trace mineral, iodine, and I recommend that you read this book: The Iodine Crisis

Important note: do not supplement with tincture of iodine – it's a poison

and this one Stop the Thyroid Madness

Your thyroid is the master gland and it requires adequate iodine to function. Make sure you know all about how the thyroid works and make sure you are not hypo-thyroid.

Please now consider the Seignalet diet

You may have already tried dietary modification for Ankylosing Spondylitis with some success, great or small - or even none at all. Regardless of the results you obtained, please now consider the Seignalet diet. This is to date, the only diet which:

A. Was trialled over a period of 20 years with over two and a half thousand patients, during which time adjustments were made in the light of results and improved theory.

B. Is the only treatment to have put into long term, complete remission about 80% of patients treated with 91 different, so called “incurable diseases”.

Dr. Jean Seignalet sets to work – the milestones

The French professor of medicine and internist at the Montpellier faculty of Medicine (in the South of France), Dr. Jean Seignalet was increasingly frustrated and irritated that medicine could still only treat the symptoms of degenerative diseases and had little idea what caused them. He was by then a leading expert and pioneer in the then new science of Human Leukocyte Antigens. (He set up and directed for 30 years a laboratory at Montpellier for HLA diagnosis of diseases for patients from all over France and for testing compatibility of kidney transplant donors and recipients and wrote two text books on HLA's). So he already knew that there was a strong genetic factor to most conditions. For example he knew that Rheumatoid arthritis patients all had a particular HLA profile.

Many day long sessions of reading and reflection

Starting in 1983, at the age of 41, Jean Seignalet set out to find the real causes of chronic, so called “incurable” diseases, with day long reading and reflection sessions in the well stocked medical faculty library. He read all the specialist medical journals: rheumatology, gastro-enterology, endocrinology, neurology, psychiatry, dermatology, opthalmology, pulmonology, oncology and of course nutrition and dietitics. He also read specialist biology journals: immunology, genetics, anthropology, bacteriology, molecular biology, and biology and physiology of ageing with a particular interest in the last one for the light it throws on cellular physiology and the small intestine, particularly the intestinal wall and gut flora.

“Fishing Trips”

He described these reading sessions as similar to fishing trips. “Most times you only catch little tiddlers but sometimes you come home with a big fish”.

Here he describes one of these big fish. “I remember for example reading a research paper which showed that gamma interferon can stick to the mucous cells of the small intestine and considerably lower the electrical resistance of the intestinal walls. That was the day I understood why psychological upsets often provoke flares in inflammatory rheumatism.” The author of this paper, said Dr. Seignalet, confined as he was to his own speciality of physiology of digestion, had no idea what an important insight this was for the field of rheumatology and furthermore, there was very little chance that a rheumatologist would ever get to read such an article, so far removed from his own speciality.

1985 - A woman with RA put into remission on the diet

By 1985, he had put together the first theoretical framework of how nutrition affects disease and was ready to try out the (then unknown but now famous, in France at least,) “Seignalet diet” on a woman with Rheumatoid arthritis. With characteristic modesty and understatement, Dr. Seignalet tells us only that the diet trial had a successful outcome with this patient with a so called “incurable” disease.

1988 -The cause of “autoimmune” disease: first theory

In 1988 he put together his initial theory on the pathogenesis (cause) of Rheumatoid arthritis and by 1990 he had revised and refined the theory and over the next five years would construct a theory to explain the cause of what he called the “clogging” diseases. For example, according to Dr. Seignalet, adult onset diabetes is a “clogging” disease. In 1992 came a further theory to explain the cause of what he called the “elimination” diseases. (Psoriasis, Crohn's, Asthma etc.) By 1994 he was ready to extend his clogging hypothesis to malignant diseases. According to Dr. Seignalet it explains two thirds of all cancers.

1996 – First edition of “Nutrition the third medicine” appears in France

In 1996 came the first edition of his book, (now famous in France), Nutrition – the third medicine which describes his theories of pathogenesis and the overwhelming successes of the diet in treating 42 different diseases. This rapidly sold out and the publisher had to quickly rush out a second edition. Only two years later came the third edition of the book, this time with results for 1,200 patients and 18 new diseases. In 2001 came the fourth edition, this time with 1,700 patients and descriptions of the treatment of a further 15 diseases and now, with sufficient time passed since treatment of the first patients had begun, able to substantiate the therapeutic effectiveness of the hypotoxic diet in many different pathologies, including some cancers.

2003 - 5th and final edition

2003 saw the 5th and final edition. (Dr. Seignalet sadly died in 2003). We find over 2,500 patients treated and a further 39 diseases. By now, enough time had elapsed since the first patients were treated to be able to draw the irrefutable conclusion of the diet's effectiveness in treating 91 different diseases. The diet had no effect on a further 12 diseases and there were another 11 diseases which were either insufficiently tested or where it was doubtful whether the diet would be effective.


Welcome to this website all about the Seignalet (pronounced “Saynyalay”) diet to reverse and prevent chronic disease. Many of the patients in Dr. Seignalet's diet trials achieved phenomenal success in overcoming a huge range of so called “incurable” diseases and the success and popularity of the diet in France is due to these recovered patients and their doctors who spread the word. Dr. Seignalet wrote a 700 page scientific treatise to explain how and why the diet works. He worked out a complete pathogenesis (cause) for most of the 91 diseases which responded to the diet. This book is in course of translation from the French and will be published around April 2016 we hope. In the meantime, a guide to Dr. Seignalet's book has been written by his daughters, one of whom is a doctor (Dr. Seignalet died in 2003). It explains the science in easy to understand terms and gets into the nitty gritty of why it works, again, in layman's language. It also gives you the full low down on how to follow the diet, with recipe and menu suggestions.

You can buy the book either in paperback or in Kindle version on amazon. If you buy the Kindle version and for any reason you are disappointed with the book's contents (we don't think you will be), you can return the book to amazon and get a full refund. The book will give you the tools you need for a recovery, hopefully a full recovery. Up to you to use them. We can't do if for you. You will find recipes and menu suggestions in the book and also in the forum on this site.

Dr. Seignalet's daughters and the French doctors, medical professors and recovered patients in the Jean Seignalet Association wish for one thing above all: for you to get well and to stay well so you can join this ever growing army of people who are free of disease.

You can buy the book called “How to prevent and reverse 100 diseases the new French way with Dr. Seignalet's diet miracle” written by Anne and Dr. Dominique Seignalet on amazon.

Please note: If you do not have a kindle and cannot afford the paperback, you can download a free app from Amazon to read the kindle version on your mac or pc.

UK & Europe
US and rest of the world

Please note: If you do not have a kindle and cannot afford the paperback, you can download a free app from Amazon to read the kindle version on your mac, pc or smartphone, iphone, android etc.

Kindle app for pc

For mac

For iphone, ipad, and ipod

For Samsung

For Android

Diseases successfully treated by Dr. Seignalet with the diet :